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McKinsey Practice Case

Hi all,

I am doing a McKinsey practice case and the second question is this: The team wants to explore BioFuture’s current drug pipeline. The team decides to focus first on evaluating the value of BioFuture’s current drug portfolio. What issues should the team consider when evaluating the value of BioFuture’s existing drug pipeline?

 

Ive interpreted this as a brainstorming question - any tips on how to structure this answer? I have to tried to structure it to cover the important points it seems somewhat messy / unstructured.

 

Thank you.

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Paul
Coach
on Oct 16, 2022
I love helping candidates prepare for their dream job at McKinsey

You have correctly identified the question as a brainstorming one. Remember when the interviewer is testing for creativity, it is vastly more important to demonstrate your ability to think creatively and comprehensively than it is to have a good structure. If you had a good structure in the first question, it won't really matter here. The biggest risk is that you have a good structure and miss some of the important issues.

With the above in mind, when I was interviewing candidates, I would consider a good approach to be:

  • Mention a few of the important issues that come to mind
  • Observe that some of these issues can be grouped into buckets/organised into a logical structure
  • Flesh out the answer and summarize/prioritize it briefly at the end

For example a good candidate might say something like:

"That's an interesting question and a number of issues come to mind such as the number of drugs in development, the types of drugs, the stage of the drugs, and regulatory issues. In fact, I think I can break this down into certain types of issues and then make a broader list under each category. Do you mind if I take a moment to structure my thoughts?"

***at this point the candidate takes a short to think and write down a few categories before continuing****

"I think one logical way of evaluating the value of BioFuture’s existing drug pipeline would be to tackle issues sequentially, based first on those issues that will affect the probability of the drugs being approved, and then analysing the issues that could affect the profitability of the drugs if they do come to market. We could then do an analysis that combines the number of drugs, their likelihood of success, and tally up the expected value

I think the main issues could be summed up like this:

1. How likely are the drugs to get to market? For each drug we might consider:

  • What types of drugs are in development and what level of expertise does BioFuture have in developing these types of drugs?
  • At what stage are the various drugs at?
  • How promising have the drugs performed at earlier stages?
  • How novel is the drug?
  • What are the main risks for each drug? 
  • What is historical success rate of similar drugs at similar stages of development?

2. If drugs are approved, how profitable are they likely to be? Again for each drug we could consider:

  • What conditions are the drugs being developed for? And what are the characteristics of those conditions (e.g. rare or common, life threatening or cosmetic, etc.)
  • What existing treatments are on the market?
  • How much investment is required to bring the drug to market?
  • What is the likelihood of a competitor bringing a new alternative to market?
  • Are their political reasons that could affect the profitability of the various drugs?

3. How valuable does the pipeline appear to be?:

  • How many drugs are in the pipeline?
  • For each drug what is their likelihood of approval and expected future value?
  • How dependent is this value on the success of a few potentially very profitable drugs? 
Erica
Coach
on Oct 10, 2022
Ex-McKinsey, former recruiting team member

This question is similar/identical to the GlobaPharm question on McK's website (the math for that question is insane so don't get caught up in that) - but regarding this question, it's certainly brainstorming since it's after the initial structure. There's no one way to do this, but since we're trying to get down to the profitability, I would break it down into risk/reward (a less cookie-cutter way of saying revenue/cost): 

Risks - how likely is pipeline to make it to market, cost to manufacture, future R&D cost, media coverage (big deal for McK)

Reward - are these drugs going to be valued, how many competitor drugs, etc

I think the biggest piece here is getting the right pieces down, and so long as the interviewer can follow you, don't worry about the “perfect” buckets - the proposed solution above certainly isn't perfect. But definitely helpful to structure brainstorms like that!

Udayan
Coach
on Oct 10, 2022
Top rated Case & PEI coach/Multiple real offers/McKinsey EM in New York /12 years recruiting experience

Whenever you look at drug pipeline there are a few things you want to look at to evaluate it : 

1. The number of drugs in development

2. The stage of development for each (which tell us the likelihood of success)

3. The type of treatment (is it novel, is it improving a current market solution, is it a stop gap due to expiring patent etc.)

4. How the treatments in the pipeline compare to (i) existing solutions and (ii) other solutions in development

5. Any perceived regulatory issues (for example if you are competing with an existing drug you need to truly demonstrate an improvement in efficiency or safety profile, similarly a novel treatment for an untreated cancer is likely to be accelerated if early phases show a lot of promise)

6. Countries where you are doing trials - US is by far the biggest market 

There are also other things to look at - e.g., the company itself and the experience they have in developing drugs, who the management team is, who the investors are etc.

 

Hope these help

Udayan

Ian
Coach
on Oct 11, 2022
Top US BCG / MBB Coach - 5,000 sessions |Tech, Platinion, Big 4 | 9/9 personal interviews passed | 95% candidate success

Hi there,

Careful - brainstorming and frameworking are essentially the same thing (an objective-driven, MECE approach). With brainstorming you still need buckets and structured thought! This question actually feels more like frameworking to me.

Option 1

Demand (projections of # affected people, WTP of them, etc.)

Supply (any new drugs expected to come onto the market, how effective they'll be in taking our share, etc.)

Option2 

Current sales/profits

Expected future sales/profits

Option 3

Market (Customer + Government)

Product (Our Drugs)

Competition (other pharma companies and their drugs)

Pedro
Coach
on Oct 24, 2022
Bain | EY-Parthenon | Former Principal | 1.5h session | 30% discount 1st session

That's not a brainstorming question (honestly, I don't think they exist). You just have to explain how to evaluate a drug pipeline.

You have to consider:

  1. Which stage the drug is in (likelyhood of success of taking the drug to market)
  2. What's the revenue potential (addressable markets x potential market share x potential margin)
  3. For how long you expect to have that revenue (IP protection, …)
  4. What are the drug's development & marketing costs and risks associated (e.g. side effects, etc.)
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